Learn more about Restylane Kysse.
Natural-looking lip enhancement
Kissable softness
- In a phase IV clinical study, 59 subjects were treated with only Restylane Kysse in the lips (n=19), or Restylane Kysse in the lips in combination with either Restylane Refyne (n=21) or Restylane Defyne (n=37) in the nasolabial folds or marionette lines.
View real people’s treatment area results after treatment with Restylane
Add fullness and definition
Learn more about Restylane Kysse.
- Actual patient. Individual results may vary.
- In a phase IV clinical study, 59 subjects were treated with Restylane Kysse in the lips (n=19) or Restylane Kysse in the lips in combination with either Restylane Refyne (n=21) or Restylane Defyne (n=37) in the NLFs or MLs.
Restylane Kysse is clinically proven to enhance lip color.6*
- Actual patient. Individual results may vary.
- *In a phase IV clinical study, 59 subjects were treated with Restylane Kysse in the lips (n=19) or Restylane Kysse in the lips in combination with either Restylane Refyne (n=21) or Restylane Defyne (n=37) in the nasolabial folds or marionette lines.test
Provides flexible support to follow lips’ natural expression1,3,5-6
Learn more about Restylane Kysse.
- Actual patient. Individual results may vary.
Explore Before & After Photos
Lip filler satisfaction
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98%of subjects were satisfied with the Kysse-ability of their lips.6*
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96%of patients agreed that their results looked natural after treatment with Restylane Kysse.6*
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3 in 4patients had visibly improved lip texture 8 weeks after treatment with Restylane Kysse.6*
Frequently Asked Questions
“Cupid’s bow” lips: The Cupid’s bow is the double curve of the upper lip, resembling the bow of Cupid, Roman god of love. Traditionally, a well-defined upper lip line is thought to help create a more beautiful lip shape.
A symmetrical pout: Typically, achieving better symmetry of the face can help to achieve a more aesthetically pleasing look. Sometimes, volume of the lips is naturally asymmetrical, or a scar or injury may have caused volume loss. Filler can be used to address symmetry of the lips and their shape.
“Natural-looking” full lips: When it comes to size and volume, a natural-looking result is key. Restylane Kysse is made with XpresHAn Technology™, for filler that moves with each smile and expression to provide more natural-looking results.1,2
Perioral lines: Also called “smoker’s lines,” “vertical lip lines,” or “barcode lines,” they develop with age and can be smoothed using filler.
Lip color and texture: Restylane Kysse is clinically proven to enhance texture and color of the lips while maintaining a full range of expressions.1,3*†
Everyone’s facial structure is different, and so are everyone’s ideal lip shape and size. Restylane-L, Restylane Silk and Restylane Kysse are designed to provide precise lip shaping and line control, resulting in natural-looking results.1,2,4,5
- Restylane Kysse. Instructions for Use. Galderma Laboratories, L.P., 2023.
- Philipp-Dormston WG, Wong C, Schuster B, Larsson M, Podda M. Evaluating perceived naturalness of facial expression after fillers to the nasolabial folds and lower face with standardized video and photography. Dermatol Surg. 2018;44(6):826-832.
- Data on file. 05DF1807 Clinical Study Report. Galderma Laboratories, L.P., 2020.
- Restylane-L. Instructions for Use. Galderma Laboratories, L.P., 2023.
- Restylane Silk. Instructions for Use. Galderma Laboratories, L.P., 2023.
†Assessed by an independent photographic reviewer (IPR).
Here are some useful tips for lip filler aftercare:
- Use cold compresses to reduce swelling.
- If you have a history of cold sores, talk with your injector before your appointment about medications that may minimize the likelihood of an outbreak. Needle punctures to the lip may increase the likelihood of cold sore reoccurrence.
- Avoid taking aspirin, nonsteroidal anti-inflammatory medications (such as ibuprofen), St. John's wort or high doses of vitamin E supplements.1,2 These agents may increase bruising and bleeding at the injection site.
- Minimize strenuous exercise and exposure to excessive heat, sun, or UV lamps for the first 24 hours after treatment. Exposure to any of these may cause temporary redness, swelling, and/or itching at the injection site. Until there is no redness or swelling, avoid exposure of the treated area to intense cold or heat such as sun lamps or sunbathing.
Remember to ask about follow-up appointments and for any additional aftercare instructions from your injector.
- Restylane Silk. Instructions for Use. Galderma Laboratories, L.P., 2023.
- Restylane Kysse. Instructions for Use. Galderma Laboratories, L.P., 2023.
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- Restylane Kysse. Instructions for Use. Galderma Laboratories, L.P., 2023.
- Restylane Silk. Instructions for Use. Galderma Laboratories, L.P., 2023.
- Restylane. Instructions for Use. Galderma Laboratories, L.P., 2023.
- Philipp-Dormston WG, Schuster B, Podda M. Perceived naturalness of facial expression after hyaluronic acid filler injection in nasolabial folds and lower face. J Cosmet Dermatol. 2020;19:1600-1606.
- Data on file. 05DF1807 Clinical Study Report. Galderma Laboratories, L.P., 2020.
- Restylane® - Instructions for Use
- Restylane-L® - Instructions for Use
- Restylane® Contour - Instructions for Use
- Restylane® Defyne - Instructions for Use
- Restylane® Kysse - Instructions for Use
- Restylane® Lyft - Instructions for Use
- Restylane® Refyne - Instructions for Use
- Restylane® Silk - Instructions for Use
- Restylane® Eyelight - Instructions for Use
- Restylane® - Patient Safety Information
- Restylane-L® - Patient Safety Information
- Restylane® Contour - Patient Safety Information
- Restylane® Defyne - Patient Safety Information
- Restylane® Kysse - Patient Safety Information
- Restylane® Lyft - Patient Safety Information
- Restylane® Refyne - Patient Safety Information
- Restylane® Silk - Patient Safety Information
- Restylane® Eyelight - Patient Safety Information
Important Safety Information
The Restylane family of products are indicated for patients over the age of 21, and includes Restylane®, Restylane-L®, Restylane® Lyft with Lidocaine, Restylane® Silk, Restylane® Kysse, Restylane® Refyne, Restylane® Defyne, Restylane® Contour, and Restylane® Eyelight.
Approved Uses
Restylane® and Restylane-L® are for mid-to-deep injection into the facial tissue for the correction of moderate to severe facial wrinkles and folds, such as nasolabial folds. Restylane® and Restylane-L® are also indicated for injection into the lips.
Restylane® Lyft with Lidocaine is for deep implantation into the facial tissue for the correction of moderate to severe facial wrinkles and folds, such as nasolabial folds and for cheek augmentation and for the correction of age-related midface contour deficiencies. Restylane® Lyft with Lidocaine is also indicated for injection into the dorsal hand to correct volume loss.
Restylane® Silk is for lip augmentation and for correction of perioral wrinkles.
Restylane® Kysse is for lip augmentation and for correction of upper perioral wrinkles.
Restylane® Refyne is for mid-to-deep injection into the facial tissue for the correction of moderate to severe facial wrinkles and folds, such as nasolabial folds.
Restylane® Defyne is for mid-to-deep injection into the facial tissue for the correction of moderate to severe deep facial wrinkles and folds, such as nasolabial folds. Restylane® Defyne is also indicated for injection into the mid-to-deep dermis (subcutaneous and/or supraperiosteal) for augmentation of the chin region to improve the chin profile in patients with mild to moderate chin retrusion.
Restylane® Contour is for cheek augmentation and for the correction of midface contour deficiencies.
Restylane® Eyelight is for the improvement of infraorbital hollowing.
Do not use if you have severe allergies with a history of severe reactions (anaphylaxis), are allergic to lidocaine or gram-positive bacterial proteins used to make hyaluronic acid, prone to bleeding, or have a bleeding disorder. The safety of use while pregnant or breastfeeding has not been studied. Tell your doctor if you have a history of scarring or pigmentation disorders as these side effects can occur with hyaluronic acid fillers. Tell your doctor if you are planning other cosmetic treatments (i.e., lasers and chemical peels) as there is a possible risk of inflammation at the injection site.
Tell your doctor if you’re taking medications that lower your body’s immune response or affect bleeding, such as aspirin or warfarin, as these medications may increase the risk of bruising or bleeding at the gel injection site. Using these products on gel injection sites with skin sores, pimples, rashes, hives, cysts, or infections should be postponed until healing is complete.
The most common side effects are swelling, redness, pain, bruising, headache, tenderness, lump formation, itching at the injection site, and impaired hand function. Delayed-onset inflammation near the site of dermal filler injections is one of the known adverse events associated with dermal fillers, and cases have been reported to occur at the dermal filler treatment site following viral or bacterial illnesses or infections, vaccinations, or dental procedures. Typically, the reported inflammation was responsive to treatment or resolved on its own. Serious but rare side effects include delayed onset infections, recurrence of herpetic eruptions, and superficial necrosis at the injection site. The risk of unintentional injection into a blood vessel is small but can occur and could result in serious complications, which may be permanent including, vision abnormalities, blindness, stroke, temporary scabs, or permanent scarring of the skin. As with all skin injection procedures, there is a risk of infection.
To report a side effect with any Restylane® product, please call Galderma Laboratories, L.P. at 1-855-425-8722.
To learn more about serious but rare side effects and full Important Safety Information, visit www.RestylaneUSA.com.